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U.S. Air Force Staff Sgt. Bianca Raleigh, 31st Medical Operations Squadron allergy and immunizations noncommissioned officer in charge, administers a patient’s shot March 23, 2015, at Aviano Air Base, Italy. In addition to providing patients with required vaccinations, the immunization clinic offers allergy shots and air allergen skin testing. (U.S. Air Force photo by Senior Airman Areca T. Wilson/Released)

HPV Vaccines

Human papilloma virus (HPV) is the most common sexually transmitted infection (STI) in the world. You may have heard that there are vaccines that can help prevent some strains of HPV. How do they work? Should you get one? Are they safe? Below is some information about HPV and the vaccines to help you decide if an HPV vaccine is right for you.

What is HPV?

  • HPV stands for human papilloma virus.
  • It is transmitted through skin-to-skin contact, particularly genital skin-to-skin contact, with someone who already has HPV.
  • There are over 100 strains (kinds) of HPV, around 40 of which affect the genital and anal (butt) area.
  • Genital HPV infections are usually cleared up by the immune system on their own over time. However, when the virus is not cleared, it remains in the body and can cause health problems.
  • Low-risk HPV can cause genital warts, little bumps that can grow on the penis*, anus (butthole) or on the outside and inside of the vagina*.
  • High-risk HPV can cause changes to the cells in the cervix (the opening to the uterus), which can lead to cervical cancer. It can also lead to anal, penile, vulvar (the genital area outside the vagina) and oral cancers.
  • The majority of people with HPV do not show any symptoms of HPV and most people don’t even know they have it.
  • It is estimated that 75% of Canadians will have HPV at some point in their lives.
  • See the HPV info page for more information [Link].

How can you get tested for HPV?

  • There is no special test for low-risk HPV (warts). A clinician can tell if you have warts by looking at any bumps you may have in and around your genitals and anus.
  • A Pap test involves a small brush that sweeps the cervix to collect a sample of cells. The cells are then examined to see if there are any abnormalities caused by high-risk HPV.
  • There is currently no test that detects changes in the cells caused by HPV inside the anus, penis, mouth, or throat.

What is the vaccine?

  • There are 2 HPV vaccines available in Canada:
    • Gardasil: This vaccine offers over 98% protection against the 4 most common strains of HPV: 2 low-risk strains (that can cause genital warts) and 2 high-risk strains (that can lead to cervical and other cancers.)
    • Cervarix: This vaccine offers over 98% protection against the 2 most common strains of high-risk HPV (that can lead to cervical and other cancers.) It does not offer protection against any strains that cause genital warts.
  • Both vaccines trigger your immune system’s response to the virus. The vaccines are not “live” vaccines, which means there is no way you can get HPV from getting an HPV vaccine.
  • Both vaccines are given by injection, usually in the upper arm.
  • A series of 3 shots are given. For Gardasil, one shot immediately, one shot 2 months later and then a final shot 4 months after that. For Cervarix, one shot immediately, one shot one month later and then a final shot 5 months after that.
  • You must have all 3 shots of the same vaccine for it to be effective. If you miss a dose, talk to your clinician – you can probably get your remaining doses without having to start over.
  • Studies show that the vaccines last for at least 5 years.
  • The most common side effects of getting an HPV vaccine are a sore arm and redness or swelling at the site of injection.
  • Less common side effects are fever, nausea, stomach upset and fainting shortly after the injection. The likelihood of having side effects is lower than with most other vaccines.
  • No serious or life-threatening side effects of the vaccines have been documented.
  • The vaccines do not treat any HPV you may already have (i.e., any existing genital warts or abnormal cervical cells).
  • The base (adjuvant) of the Gardasil vaccine is aluminum hydroxyphosphate. The Cervarix vaccine is also aluminum based. Research has found that the quantities of the bases used in the vaccines are not harmful to people.

Who can get an HPV vaccine?

  • In Canada, the Gardasil vaccine is approved for people with ovaries** 9-45 years of age and people with testicles** 9-26 years of age.
  • The Cervarix vaccine is approved for people with ovaries 10-25 years of age.
  • If you are interested in a vaccine but you don’t fit these categories, talk to your clinician.
  • In Ontario, the Gardasil vaccine is offered free of charge to people with cervixes that are in Grade 8 in schools only (the cost is covered by OHIP).
  • For everyone else, the cost of the Gardasil vaccine is approximately $150 per dose, plus dispensing fees and taxes (just under $500 total for all 3 shots). Cervarix is approximately $90 per dose, plus dispensing fees and taxes (just under $350 for all 3 shots). You can only purchase one dose at a time.
  • Both vaccines are covered by many insurance plans. To check, you will need the DIN (drug identification number). The DIN for Cervarix is: 02342227 and the DIN for Gardasil is: 02283190.

Should I get an HPV vaccine?

  • It is important that you make your decision based on good information and according to your own values.
  • The best time to get the vaccine is before you’ve become sexually active. However, the vaccine is still useful for people who are already sexually active. The likelihood that someone who is sexually active has already had all of the strains of HPV that either of the vaccines prevent is approximately 1/1000.
  • Do not get the vaccines if you are or may be pregnant.
  • The plunger used with Cervarix contains latex and may not be suitable for anyone with a latex allergy. Gardasil is latex-free.

Where can I get an HPV vaccine?

  • You can get a vaccine from a clinician. They will write a prescription for you. You take that prescription to the pharmacy, purchase the vaccine, and bring it back to your clinician to receive the injection. You will do this a total of 3 times, once per shot.
  • If you are not going directly from the pharmacy back to your clinician to get the vaccine injected, talk to the pharmacist about how to store the vaccine properly.
  • The Bay Centre for Birth Control has an HPV vaccine clinic every Tuesday afternoon where you can buy and receive either HPV vaccine. Call 416-351-3700 to book an appointment.


  • If you have a cervix, you still need Pap tests even if you get an HPV vaccine.
  • The vaccine does not protect you from other STIs or the strains of HPV not covered by the vaccine.
  • Make informed decisions. Talk to your partner(s) about STIs and the use of safer sex tools.
  • Use condoms on penises or dildos for vaginal or anal sex, use latex gloves for finger play and use condoms/dams for oral sex to lower your chances of getting STIs.

Download Planned Parenthood Toronto’s info pamphlet on this subject: HPV Vaccines

*We know that these aren’t the words everyone uses for their bodies (eg. trans folks), and support you using the language that feels best for you.

** People with cervixes are usually designated female at birth while people with testicles are usually designated male at birth. People with testicles don’t always identify as male and people with cervixes don’t always identify as female.